Paclitaxel Devices Safe in PAD In Medicare Data Beyond 3 Years
ATLANTA — Paclitaxel-coated devices for femoropopliteal artery revascularization were not associated with any excess mortality risk in the latest update from Medicare data. The risk of death from any cause, if anything, trended slightly lower (hazard ratio 0.98, 95% CI 0.96-0.99) with paclitaxel-eluting stents or -coated balloons compared with bare metal stent or percutaneous transluminal […]
Osilodrostat Resolves Most Physical Signs of Cushing’s Disease
SAN DIEGO — Osilodrostat (Isturisa) improved many physical features associated with Cushing’s disease, according to additional findings from the phase III LINC-3 study. Among 137 adults with Cushing’s disease, a 39.5% improvement in central obesity scores was observed from baseline to week 72 with osilodrostat, reported Alberto Pedroncelli, MD, PhD, of Recordati AG in Basel, […]
Flu causes cardiac complications by directly infecting the heart: In mouse study, heart is unaffected by lung inflammation alone
Researchers have shown for the first time in mice that heart problems associated with the flu are not caused by raging inflammation in the lungs, as has long been predicted. Instead, the Ohio State University study revealed, the electrical malfunctions and heart scarring seen in some of the sickest flu patients are caused by direct […]
Did a Singing-Based Program Hit the Right Notes for Long COVID Patients?
An online singing-based program from the English National Opera (ENO) was associated with improvements in quality of life among adults with long COVID, a pragmatic randomized trial in England showed. Compared with usual care, the 6-week ENO Breathe program was associated with improvements in mental health composite scores on the RAND 36-item short form survey […]
How Can I Improve My Winter Mood? Diet & Exercise
What nutrients are essential for beating winter blues? Winter is often associated with certain nutritional deficiencies, such as vitamin D deficiency. Addressing these deficiencies and including certain foods in your diet may help beat the winter blues. Vitamin D There are conflicting reports about the link between low vitamin D levels and low mood. However, […]
Poor diet associated with increased diabetes risk across all gradients of genetic risk: A poor diet, irrespective of genetic risk factors, is associated with a 30 percent increased risk of diabetes
Genetic risk factors and diet quality are independently associated with type 2 diabetes; a healthy diet is linked to lower diabetes risk across all levels of genetic risk. That’s the conclusion of a study of more than 35,000 US adults publishing April 26 in PLOS Medicine by Jordi Merino of Massachusetts General Hospital, US, and […]
Study finds infertility history linked with increased risk of heart failure: The future risk of heart failure is not related to other known factors
A new study finds that a history of infertility is associated with increased risk of heart failure. Published in the Journal of the American College of Cardiology, researchers from Massachusetts General Hospital (MGH) revealed that women who had experienced infertility had a 16% increased risk of heart failure compared with women who did not have […]
Blood Biomarker Linked With Parkinson’s Disease
Serum neurofilament light (NfL), a measure of axonal injury, was associated with incident Parkinson’s disease, parkinsonian signs, and decline in physical functioning, a longitudinal study showed. Among 1,300 people in the Chicago Health and Aging Project (CHAP), a twofold higher concentration of serum NfL was associated with incident clinical Parkinson’s disease (OR 2.54, 95% CI […]
High cardiovascular risk is associated with symptoms of depression: Improving cardiovascular health might help prevent the onset of depression in the elderly, researchers say
Cardiovascular risk factors are associated with an increased risk of depression in older adults, according to a new study published April 13 in the open-access journal PLOS ONE by Sandra Martín-Peláez of University of Granada, Spain, and colleagues. Cardiovascular disease and depression are thought to be closely related due to similar risk factors, including inflammation […]
COVID-19 Tied to High Risk of Thrombotic Events
COVID-19 was associated with a greater risk for a host of thrombotic events in the months following a patient’s infection, a large study in Sweden found. Among over 1 million people who tested positive for COVID-19 in the past month, risk for a first pulmonary embolism was 33 times higher compared with a matched control […]