Mortality Risk From Damaged Bronchi Extends to People Without COPD
Bronchiectasis was associated with an increased mortality risk in current and former smokers even if they did not meet the spirometric criteria for chronic obstructive pulmonary disease (COPD), an observational study found. Compared with patients without suspected bronchiectasis, the 10-year mortality risk was greater among patients who had suspected bronchiectasis — evidenced by CT and […]
Study Confirms Better Survival for HPV-Positive Cervical Cancer
Cervical cancer associated with detectable human papillomavirus (HPV+) RNA or DNA had significantly better outcomes, including survival, a large meta-analysis of published studies showed. Patients who tested positive for HPV had a 62% improvement in disease-free survival (DFS), 44% improvement in cancer-specific survival (CSS), and 41% improvement in overall survival (OS), as compared with patients […]
Reduced Mortality Seen in Cancer Survivors Who Meet Exercise Guidelines
Exercise consistent with national guidelines was associated with a significant reduction in all-cause mortality in long-term cancer survivors, a pan-cancer analysis showed. In a study involving 11,480 survivors, guideline-concordant exercise was associated with a 25% reduced risk of all-cause mortality compared with no exercise (HR 0.75, 95% CI 0.70-0.80) at a median follow-up of 16 […]
Fresh Blood Not Always the Best Blood?
Longer storage of red blood cell (RBC) units was associated with longer transplant survival in kidney transplant patients receiving early transfusions, a retrospective study in France found. Among 3,483 kidney recipients who received RBC transfusions within 14 days posttransplant, each additional day of RBC storage was associated with a non-significant 1% reduction in the risk […]
One PrEP Regimen Linked to Higher Risk of Hypertension, Statin Use Over Another
Use of tenofovir alafenamide fumarate (TAF) for HIV pre-exposure prophylaxis (PrEP) was associated with an increased risk of hypertension and the initiation of statin use within 2 years compared with the use of tenofovir disoproxil fumarate (TDF; Viread), especially for people over age 40, a retrospective cohort study found. In a cohort of patients without […]
Common Food Additives Singled Out for Cardiovascular Risk
Food additive emulsifiers were individually associated with modest increases in cardiovascular disease (CVD) in a large French epidemiological cohort, researchers found. Various types of emulsifiers — widely used to keep oils and water mixed together and prolong the shelf-life of processed foods — were positively associated with higher risks of CVD and coronary heart disease […]
Use of E-Cigs Alone Linked to Respiratory Symptoms
Use of e-cigarettes may be inherently associated with respiratory issues regardless of traditional cigarette or cannabis exposure, a prospective study found. Teenagers who reported using e-cigarettes in the previous 30 days subsequently reported an increased risk for shortness of breath (OR 1.78, 95% CI 1.23-2.57), wheezing (OR 1.81, 95% CI 1.28-2.56), and bronchitic symptoms (OR […]
Irregular sleep patterns associated with harmful gut bacteria
New research has found irregular sleep patterns are associated with harmful bacteria in your gut. The study, published today in The European Journal of Nutrition, by researchers from King’s College London and ZOE, the personalised nutrition company, is the first to find multiple associations between social jet lag — the shift in your internal body […]
Pegcetacoplan-Related Eye Inflammation: The Search Is on for Answers
SEATTLE — Reports of unexpected panuveitis and retinal occlusive vascular disease associated with pegcetacoplan (Syfovre) treatment has triggered a search for answers by ophthalmologists and the drug’s manufacturer. Since July 3, the American Society of Retina Specialists (ASRS) Research and Safety in Therapeutics (ReST) Committee has learned of seven cases of retinal inflammation and vascular […]
Protein found to protect females against obesity
Associated with poorer mental health outcomes and reduced quality of life, obesity is on the rise in the United States. Currently, more than 30% of American adults are classified as obese. A risk factor for several diseases, including diabetes, cardiovascular disease, and COVID-19, obesity is an important and growing public health concern. Using a mouse […]