Bedtime linked with heart health
Going to sleep between 10:00 and 11:00 pm is associated with a lower risk of developing heart disease compared to earlier or later bedtimes, according to a study published today in European Heart Journal — Digital Health, a journal of the European Society of Cardiology (ESC). “The body has a 24-hour internal clock, called circadian […]
Brain reveals the risk for developing obesity
Obesity risk factors of family background are associated with changes in the brain function, finds a study conducted at the Finnish Turku PET Centre. The results show that the function of neural networks regulating satiety and appetite is altered already before a person develops obesity. Obesity is a globally increasing health problem, and new interventions […]
Risk of Premature Death Seen in Testicular Cancer Survivors
Treating testicular cancer (TC) with platinum-based chemotherapy (PBCT) and radiotherapy (RT) was associated with an increased risk of long-term non-TC mortality, a Norwegian population-based cohort study found. Over a median follow-up of 18.7 years, overall excess non-TC mortality was 23% in men diagnosed with TC compared with the general population (standardized mortality ratio [SMR] 1.23, […]
Good sleep-time recovery is associated with a healthier diet and lower alcohol consumption
Good sleep-time recovery is associated with a health-promoting diet and health-promoting eating habits, as well as with lower consumption of alcohol, according to a new study investigating psychological and physiological well-being among working-age Finnish adults. The association of physiological recovery with nutrition has been studied only scarcely. Published in Journal of Occupational Medicine and Toxicology, […]
Imaging single spine structural plasticity at the nanoscale level
For most, the relentless snapping of camera shutters is an all too familiar sound associated with trips and vacations. When venturing to a new place, travelers everywhere are constantly on the search for that picture-perfect, Instagram worthy shot. Persevering through many takes, amateur photographers fight blurred backgrounds, closed eyes, and photo-bombing passersby all in search […]
Maybe Avoid These Specialists for Your Next Colonoscopy
Colonoscopies performed by surgeons and other endoscopists were associated with lower adenoma detection rates compared to those done by gastroenterologists, according to a meta-analysis. In a systematic review of 36 studies, adenoma detection rates during colonoscopy were 19% lower with surgeons (OR 0.81, 95% CI 0.74-0.88) and 9% lower with family physicians, general practitioners, and […]
Robot-Assisted Prostatectomy Tied to Fewer Complications
Robot-assisted radical prostatectomy (RARP) was associated with fewer surgical complications compared with open or laparoscopic prostatectomies, a population-based cohort study in Taiwan found. Among more than 1,400 patients who underwent radical prostatectomy in 2015, those treated with RARP were less likely to need blood transfusions compared with those who received laparoscopic radical prostatectomy (LRP; adjusted […]
Rheumatic Events With Checkpoint Inhibitors: Tumor Type Matters
Among the factors that were associated with an increased risk for the development of rheumatic immune-related adverse events following cancer treatment with immune checkpoint inhibitors (ICIs) was the type of malignancy involved, a large case-control study found. Compared with reference lung cancer (the most common type of malignancy in this cohort), the development of a […]
FDA Approves First Drug for Von Hippel-Lindau-Associated Tumors
The FDA has approved the first therapy for cancers associated with von Hippel-Lindau (VHL) disease. Belzutifan (Welireg), distributed by Merck, targets hypoxia-inducible factor 2α, which drives growth of malignant and benign tumors in VHL. In the absence of approved systemic therapies, most patients with VHL undergo multiple surgeries in their lifetime to remove renal cell […]
Full-Dose Heparin Benefit in Certain COVID-19 Patients Confirmed
A therapeutic dose of heparin was associated with increased probability of survival for non-critically ill COVID-19 patients versus usual-care thromboprophylaxis, but not for the most severe patient population, peer-reviewed results from the REMAP-CAP, ACTIV-4a, and ATTACC multi-platform trial showed. In the non-critically ill cohort, therapeutic dose anticoagulation with heparin was superior to usual care prophylaxis, […]