New Data on BCMA-Directed Bispecifics in Multiple Myeloma
Promising data on new B-cell maturation antigen (BCMA)-directed bispecific antibodies were presented at the American Society of Clinical Oncology (ASCO) annual meeting. These included results on two investigational products: the phase II LINKER-MM1 study, which showed that linvoseltamab elicited an objective response rate of 71% at the recommended dose of 200 mg for patients with […]
Monoclonal Antibodies Linked to Reduced RSV Burden in Young Kids
Prophylactic use of three monoclonal antibodies was associated with substantial reductions in respiratory syncytial virus (RSV)-related infections and hospitalizations in children under 5, a systematic review and meta-analysis showed. Across 14 randomized controlled trials involving over 18,000 high-risk children, moderate- to high-certainty evidence showed that nirsevimab, palivizumab, and motavizumab were associated with significant reductions in […]
XBB Variant Up to 21 Times More Evasive to Vaccine Antibodies Than BA.5
Omicron subvariants BQ.1.1 and XBB.1 were more effective at escaping neutralizing antibodies compared with the BA.5 variant following both monovalent and bivalent mRNA boosters, new data suggested. In 15 participants who had received a monovalent mRNA booster in 2022, neutralizing antibody titers against BA.5 were seven times higher than those for BQ.1.1, and 17 times […]
Artificial intelligence system rapidly predicts how two proteins will attach: The machine-learning model could help scientists speed the development of new medicines
Antibodies, small proteins produced by the immune system, can attach to specific parts of a virus to neutralize it. As scientists continue to battle SARS-CoV-2, the virus that causes Covid-19, one possible weapon is a synthetic antibody that binds with the virus’ spike proteins to prevent the virus from entering a human cell. To develop […]
Can Lyme Disease Be Detected by a Blood Test?
Lyme disease can be detected by tests that look for antibodies in the blood. Learn more about Lyme disease testing, stages, and symptoms Lyme disease can be detected by tests that look for antibodies in the blood or in the fluid from the joints or spine. However, antibodies can take 4-6 weeks to be detected […]