No Negative Neurodevelopmental Issues With Late Exposure to Antenatal Steroids
SAN FRANCISCO – Giving late preterm antenatal corticosteroids did not impact childhood neurodevelopmental outcomes, a researcher reported. In a follow-up to the ALPS study, there were no statistically significant differences in the scores of children exposed to corticosteroids or to placebo in the third trimester based on cognitive testing, according to Cynthia Gyamfi-Bannerman, MD, of […]
Prenatal Steroids May Improve Outcomes in Extremely Preterm Infants
A complete course of antenatal steroids was associated with higher survival in extremely preterm infants, a cohort study showed. Among infants born at 22 weeks to less than 24 weeks, 53.9% who had full exposure to antenatal steroids at gestational age 21 to 22 weeks survived to discharge, compared with 37.5% who had partial steroid […]
Lowering Antenatal Betamethasone Dose Misses in Randomized Trial
Cutting the dose of antenatal betamethasone in half was not equivalent to full-dose antenatal betamethasone when it came to needing to treat respiratory distress in very preterm infants, findings from the randomized BETADOSE trial showed. Among more than 3,000 neonates in the intention to treat (ITT) analysis, 20% of newborns in the half-dose group required […]