Global Suicides Rise; Outgrowing ADHD; A 40-Year Soda Addiction
Over the past 30 years, global suicide deaths rose by almost 20,000, with most countries seeing the highest suicide rates in people ages 70 and older. (Injury Prevention) The FDA cleared BrainsWay’s Deep Transcranial Magnetic Stimulation (TMS) system for anxious depression, the company announced. The TMS system was already indicated for major depressive disorder, obsessive-compulsive […]
Slow Going With CAR T-Cell Therapy for Solid Tumors
Almost 4 years after the first chimeric antigen receptor (CAR) T-cell therapies received FDA approval, the transformative impact of the treatment on refractory hematologic malignancies has yet to translate into the field of solid tumors. The increased molecular complexity of solid tumors and lack of good antigen targets have coalesced into a formidable roadblock for […]
Safety Concerns Turn FDA Panel Thumbs Down for Novel CKD-Anemia Drug
An FDA advisory committee almost unanimously agreed that the risks were just too high for the chronic kidney disease (CKD)-related anemia drug roxadustat in any patient population. In a 13-1 vote Thursday, members of the Cardiovascular and Renal Drugs Advisory Committee felt that although there’s an unmet need for new anemia therapeutics, this particular drug […]
Physicians: Stop Dreading Call
Even though I completed residency almost 15 years ago, it is easy to remember the dread I experienced before taking hospital call. The sinking feeling in my stomach as the call date loomed near, the hypervigilance and terror every time my beeper went off in the middle of the night, the fear of imagined catastrophes […]