Linaclotide Eases Abdominal Symptoms in IBS With Constipation
Linaclotide (Linzess) significantly alleviated abdominal symptoms in irritable bowel syndrome (IBS) patients with predominant constipation compared with placebo, researchers found in a randomized study. Using an abdominal score that averaged abdominal bloating, discomfort, and pain on an 11-point scale, the average overall change from baseline was -1.9 for patients treated with linaclotide and -1.2 for […]
Psychedelics for Psych Conditions Made Their Mark in 2023
In January, we reported on an investigational psychedelic that alleviated symptoms of depression in a mid-stage trial. In this report, we follow up on what has happened since that study was published. In the phase IIa trial, an investigational N,N-dimethyltryptamine treatment — commonly known as the hallucinogen DMT — significantly reduced depressive symptoms by 7.4 […]