Tailoring Drug Interaction Alerts to the ICU Reduced Number of High-Risk Combos
PHOENIX — Tailoring potential drug-drug interaction (DDI) alerts to the intensive care unit (ICU) setting significantly reduced the number of administered high-risk drug combinations, a cluster randomized stepped-wedge trial showed. Among nearly 10,000 patients admitted to the ICU, the use of potential DDI alerts tailored to the ICU led to a 12% decrease (95% CI […]
Mixed Results With Alerts for AKI-Related Medications in Hospital
While medication-targeted acute kidney injury (AKI) alerts led to certain kidney-affecting medications being stopped, the overall clinical impact was limited, a researcher reported. The open-label, randomized trial included over 5,000 patients hospitalized for AKI with an active order for one of the medication of interest (MOIs) classes that were selected as being possibly nephrotoxic — […]