Dupilumab Cuts Lung Inflammation, Breaks Up Mucus Plugs in Asthma Patients
WASHINGTON — Dupilumab (Dupixent) reduced airway inflammation and increased lung capacity in patients with uncontrolled, moderate-to-severe asthma, while also reducing troublesome mucus plugs, a multinational postmarketing study showed. In the randomized study, treatment with dupilumab led to significant reductions in airway inflammation at 24 weeks, with 57% achieving a fractional exhaled nitric oxide (FeNO) level […]
CPAP Turns in Mixed Results for Patients With Diabetic Eye Disease
Long-term use of continuous positive airway pressure (CPAP) slowed the progression of eye disease in sleep apnea patients with non-proliferative diabetic retinopathy, a small randomized study showed, but patients who adhered to the intervention ended up with more retinal microhemorrhages. In the single-center trial, the group assigned to a year of CPAP atop usual care […]
Positive Airway Pressure Linked to Less Late-Night Heart Burn Problems
Positive airway pressure (PAP) treatment for obstructive sleep apnea (OSA) was linked to reduced respiratory symptoms and nocturnal gastroesophageal reflux (nGER), an Icelandic study found. After 2 years, full PAP users reported a decrease in both nGER (adjusted odds ratio [aOR] 0.58, 95% CI 0.40-0.86) and wheezing (aOR 0.56, 95% CI 0.35-0.88) compared with non-users, […]
Study: Not Sticking to Schedule Shouldn’t Block PAP Machines for Kids With OSA
CHARLOTTE, N.C. — Positive airway pressure (PAP) machines were helpful enough that pediatric patients could have symptoms improve even without being compliant, according to researchers advocating for greater access to this therapy for this population. At one center’s sleep clinic, 172 out of 221 children with obstructive sleep apnea (OSA) reported improved symptoms approximately 3 […]