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Time for Targeted PSA Screening for Men With Rare Pathogenic Variants?

Men with certain pathogenic variants had a higher incidence of prostate cancer versus age-matched controls, and may be candidates for targeted prostate-specific antigen (PSA) screening, according to findings from the IMPACT trial. In the international, prospective study, men with confirmed pathogenic variants in mismatch repair (MMR) genes who underwent one screening round had a higher […]

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