RT After Breast-Conserving Surgery Shows No Survival Advantage Decades Later
Radiotherapy after breast-conserving surgery for early breast cancer substantially reduced the risk of disease recurrence, yet the benefit did not translate to an improvement in overall survival (OS) at 30 years, a long-term analysis of the Scottish breast conservation trial showed. Compared with no radiotherapy, adjuvant locoregional radiotherapy reduced the risk of ipsilateral breast tumor […]
Study Suggests Potential to Skip Surgery for Selected Breast Cancer Patients
Women who chose not to have surgery after a pathologic complete response (pCR) to neoadjuvant therapy for early HER2-positive or triple-negative breast cancer (TNBC) had no recurrences during the first 2 years of follow-up, a small prospective study showed. Overall, 31 of 50 (62%) women had no evidence of residual disease by image-guided vacuum-assisted core […]
About 1,000 Students At A Virginia High School Have Come Down With ‘Flu-Like’ Symptoms
A high school in Virginia had to cancel its weekend activities after nearly half its students came down with flu-like symptoms. “There are approximately 1,000 students absent with flu-like/gastrointestinal symptoms at Stafford High School,” Sandra K. Osborn, chief communications officer with Stafford County Public Schools, said in a statement. “Our Health Services team is working […]
Katie Couric’s Breast Cancer
In 2000, 2 years after the death of her husband, Jay Monahan, from colon cancer, Katie Couric underwent a colonoscopy live on “The Today Show,” leading to a 20% jump in national colonoscopy screening rates, something the University of Michigan dubbed the “Couric Effect.” Now, Couric is once again advocating for cancer screening. On September […]
Opinion | Physicians: Get a Mentor or a Coach?
Over the years, I have mentored a lot of trainees. After discovering coaching and seeing my career transform after I started working with a coach, I have become a coach myself. I definitely use coaching techniques with my mentees, but the relationship I have with them is different from the one I have with my […]
Long-Term Neurologic Problems Rise by 7% After SARS-CoV-2 Infection
Risk of movement disorders, memory problems, strokes, and seizures rose 1 year after acute SARS-CoV-2 infection, an analysis of millions of U.S. veterans’ records showed. Former COVID patients had a 42% increased risk of neurologic problems 12 months after testing positive (HR 1.42, 95% CI 1.38-1.47), reported Ziyad Al-Aly, MD, of Washington University in St. […]
Presumed Clinical Benefits of TAVR Cerebral Protection Remain Unproven
BOSTON — Cerebral embolic protection (CEP) again came up empty in preventing strokes after transcatheter aortic valve replacement (TAVR) despite safely capturing embolic material dislodged during the procedure, a large randomized trial found. In the 3,000-person PROTECTED TAVR trial, the sentinel dual-filter system produced no significant reduction in periprocedural strokes compared with control cases without […]
Long-Term ADT With Radiation Helps Prevent Post-Prostatectomy Metastases
PARIS — In men undergoing radiotherapy after radical prostatectomy, 2 years of androgen deprivation therapy (ADT) improved outcomes when compared with a shorter course of ADT, according to results from the RADICALS-HD trial. At a median follow-up of more than 9 years, investigators found that the longer ADT duration improved metastasis-free survival (MFS) compared with […]
Texas Reports Nation’s First Possible Death From Monkeypox
A severely immunocompromised man in Texas has died after being diagnosed with monkeypox, state and local health officials announced Tuesday, marking what may be the nation’s first death related to the disease. Harris County Judge Linda Hidalgo said in a statement that the Houston-area man, who died Sunday, “faced various severe illnesses” and that his […]
Routine Stress Testing Didn’t Offer Benefits to High-Risk Patients Post-PCI
BARCELONA – Routine functional testing after percutaneous cardiac interventions (PCI) did not boost clinical outcomes at 2 years in high-risk patients, according to the POST-PCI trial. The composite endpoint of death from any cause, myocardial infarction, or hospitalization for unstable angina was experienced by 5.5% of patients who got routine functional testing versus 6.6% in […]