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Serious Issues With Slow Heartbeat Flagged for Afib Patients on Antiarrhythmics

Old concerns about the safety of rhythm control drugs for atrial fibrillation (Afib or AF) resurfaced in a contemporary large Korean population-based study. Afib patients prescribed antiarrhythmic drugs (AADs) had several-fold higher risks of cardiac events believed to be related to a decline in heart rate. Compared with other Afib patients, these AAD users showed […]

DOAC Cuts Stroke Risk From Subclinical Afib

PHILADELPHIA — For patients with subclinical atrial fibrillation (Afib, AF) detected by their pacemaker or defibrillator, direct oral anticoagulation brought their already low stroke risk even lower — but at a cost in bleeding events, the ARTESiA trial showed. Apixaban (Eliquis) treatment cut risk of stroke or systemic embolism 37% compared with low-dose aspirin over […]

Consequences of Oral Anticoagulant Choice Magnified in the Frail

Older adults with atrial fibrillation (Afib, or AF), especially those with frailty, had better patient-centered outcomes taking apixaban (Eliquis) than other common oral anticoagulants (OACs), Medicare records showed. Compared with apixaban, rivaroxaban (Xarelto) was associated with significantly increased risk of spending more than 14 days in the hospital or a skilled nursing facility during follow-up […]

Ablation, CRT Boost Survival in Permanent Afib With Narrow QRS

A “pace-and-ablate” strategy substantially boosted survival for permanent atrial fibrillation (Afib) patients with a narrow QRS across the range of left ventricular ejection fraction (LVEF), the APAF-CRT trial showed. While relatively small with 133 patients after being stopped early for efficacy at a median 29 months of follow-up, the trial showed a relative 74% survival […]

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