Mutation Linked to Increased Risk of Prostate Cancer Mortality
The risk of dying of prostate cancer doubled in the presence of a genetic mutation affecting testosterone production, a large prospective cohort study showed. The 5-year risk of prostate cancer-specific mortality (PCSM) increased from 1.7% to as much as 4%, depending on the genotype of the HSD3B1(1245C) allele. In a subgroup of patients with metastatic […]
Neurologic Conditions Now Leading Cause of Disability Worldwide
Disorders affecting the nervous system were the leading cause of ill health and disability globally, affecting 3.4 billion people worldwide, a systematic analysis for the Global Burden of Disease (GBD) Study showed. Neurologic conditions affected 43.1% of the world’s population and were the top contributor to the global disease burden in 2021, ahead of cardiovascular […]
Clinical Challenges: Early Disease in Axial Spondyloarthritis
Axial spondyloarthritis (axSpA) is the currently favored term for a spectrum of painful disorders affecting the spine, and most specifically the sacroiliac joints. Its prototypical form was ankylosing spondylitis, defined some 40 years ago as a condition characterized by the presence of radiographic sacroiliitis. However, ankylosing spondylitis today is considered a misnomer because while it […]
New Monkeypox Cases Plummet, but Racial Gap Remains, White House Says
WASHINGTON — Cases of monkeypox are continuing to decline in the U.S., but the disease is still disproportionately affecting people of color, a White House official said. “In the U.S., about 27,635 cases were reported as of yesterday,” Demetre Daskalakis, MD, White House National Monkeypox Response deputy coordinator, said at an online briefing Thursday. “We […]