Keto for Kids With Diabetes Carries Risk, AAP Warns
Keto and other low carbohydrate diets have gained popularity for type 2 diabetes in adults, but there are safety concerns for young people, the American Academy of Pediatrics (AAP) cautioned. Restricting carbohydrates in young people at risk for or with diabetes raises concerns for growth deceleration, nutritional deficiencies, poor bone health, nutritional ketosis, and disordered […]
Ultra-Rare Immune System Disease Gets First FDA-Approved Treatment
The FDA approved pozelimab (Veopoz) as the first treatment for adults and children ages 1 year and up with CD55-deficient protein-losing enteropathy. Also known as CHAPLE (complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy) disease, CD55-deficient protein-losing enteropathy is an inherited disease marked by mutations of the complement regulator CD55 gene, which causes the complement system […]
FDA Gives Nod to Gene Therapy for Hemophilia A
The FDA approved valoctocogene roxaparvovec (Roctavian) as the first gene therapy for the treatment of adults with severe hemophilia A, drug developer Biomarin announced on Thursday. Patients with severe disease are eligible for the one-time, single-dose treatment if they don’t have antibodies to adeno-associated virus serotype 5 (AAV5), as detected by an FDA-approved test. FDA […]
FDA Greenlights New Myasthenia Gravis Drug
The FDA approved rozanolixizumab-noli (Rystiggo), a neonatal Fc receptor blocker, to treat adults with generalized myasthenia gravis (gMG), UCB announced Tuesday. The drug is the first approved to treat both of the two most common subtypes of gMG patients — those who are anti-acetylcholine receptor (AChR)-positive and those who are anti-muscle-specific tyrosine kinase (MuSK) antibody-positive. […]
The 9 Biggest Signs Of Autism In Adulthood
Westend61 via Getty Images Internally, many undiagnosed adults with autism say they feel different from those around them. You may have seen videos on social media where people detail the signs that made them realize they’re autistic. Viewers are finding them enlightening and comforting as many people — mainly women — are undiagnosed as they […]
Behavior patterns of people who achieve clinically significant weight loss: Study finds widespread poor adoption of heart-healthy measures in US adults
A new study analyzing data on over 20,000 U.S. adults links a healthier diet and increased exercise to weight loss that reduces heart disease risk — while associating skipping meals and taking prescription diet pills with minimal weight loss, weight maintenance or weight gain. For many in the study sample, however, losing a “clinically significant” […]
Researchers leverage cell self-destruction to treat brain tumors
Glioblastoma is the most common type of brain tumor in adults. The disease is 100% fatal and there are no cures, making it the most aggressive type of cancer. Such a poor prognosis has motivated researchers and neurosurgeons to understand the biology of tumors with the goal of creating better therapies. Dominique Higgins, MD, PhD, […]
Novel Drug Authorized for Critically Ill COVID-19 Patients
The FDA has issued an emergency use authorization (EUA) for vilobelimab (Gohibic) to treat critically ill adults with COVID-19. In the EUA for the first-in-class monoclonal anti-human complement factor C5a antibody, the agency specified that the therapy be initiated within 48 hours of invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO). It is given at […]
Paxlovid May Lower Long COVID Risk, VA Study Suggests
Use of nirmatrelvir-ritonavir (Paxlovid) in older adults with risk factors for severe disease was associated with a roughly 25% lower risk of a post-COVID condition (PCC), a retrospective study of Veterans Affairs data showed. In the cohort of over 280,000 patients with a confirmed COVID case, 13% of those prescribed nirmatrelvir-ritonavir went on to develop […]
Excess calories during development alters the brain and spurs adult overeating
People whose mothers are overweight during pregnancy and nursing may become obese as adults because early overnutrition rewires developing brains to crave unhealthy food, according to a Rutgers study in Molecular Metabolism. Rutgers researchers traced this link from mother to child in mice with an experiment that began by letting some mice get obese on […]