Study Validates Accuracy of PREDICT Prognostication Tool in Breast Cancer
The PREDICT prognostication tool was able to estimate overall survival (OS) with decent accuracy in a large independent U.S. dataset of breast cancer patients, researchers reported. From more than 700,000 patients in the National Cancer Database (NCDB), the free online tool estimated median and mean 5-year OS rates ranging from 83.3% to 84.4%, as compared […]
Infant Boys Better at Resisting HIV Than Girls?
BRISBANE, Australia — Infant boys appeared more likely than girls to be able to resist in utero vertical transmission of HIV, even when their mothers had less than optimal antiretroviral therapy, a longitudinal study showed. Of 281 mother-child pairs, five babies — all boys — had persistently undetectable HIV viral loads even when they were […]
The 1 Thing That Child Therapists Say Harms Kids’ Happiness The Most
Children and adolescents in the U.S. today reap the benefits of decades of medical and psychological research. We are able to diagnose and effectively treat mental health conditions to a degree that wasn’t possible only a generation ago, with a wider arsenal of pharmacological options and increasingly targeted and sophisticated non-invasive therapies. The quality of […]
Accelerated Approval Not the Finish Line, Says FDA Commissioner
Drugmakers will no longer be able to slow-walk their accelerated approvals to full regulatory approval, said FDA Commissioner Robert Califf, MD, during the J.P. Morgan Healthcare Conference on Tuesday, while also fielding questions on gene therapies and the modernization of clinical trials, among other topics. Accelerated Approval When asked about the kind of data needed […]
Cutting Unneeded Urine Cultures a Good First Step to Less Antibiotic Use
WASHINGTON — Michigan hospitals were able to cut down on unnecessary treatment of asymptomatic bacteriuria (ASB) thanks to better diagnostic stewardship, according to a study. The percentage of patients with a positive urine culture who had ASB fell from 34.1% in the year 2017 to 22.5% in 2020 in a consortium of 46 hospitals. That […]
Opinion | Santa Claus, the Tooth Fairy, and Death
More than ever these days, we aren’t able to hide death from children. Whether we’re addressing their fear around school shootings, natural disasters, grief from family members lost during the COVID-19 pandemic, or concerns about their own illness, it’s impossible to shield kids from bearing witness to illness and death — nor should we. So, […]
Opinion | ‘The Universe Made a Hard Decision on My Behalf’: What We Heard This Week
“My disbelief was quickly replaced by relief and immense gratitude at being able to pursue my dreams on my own terms. In so many ways, the universe made a hard decision on my behalf.” — Travis Hughes, PhD, MPH, on the brighter side of not matching into residency. “The hospital is not and should not […]
Stem cell secrets allow researchers to revamp reprogramming: Researchers have identified factors required to generate naïve stem cells by reprogramming
Researchers from the Babraham Institute’s Epigenetics research programme have been able to learn more about naïve stem cell reprogramming following a genome wide functional screen. Their research, published today in Science Advances, describes the critical regulators of reprogramming and offers opportunities for a more efficient, faster way to generate human naïve pluripotent stem cells. Human […]
‘We Are Turning a Corner on COVID’: HHS Secretary Calls for More Funding
WASHINGTON — In order to be able to turn the corner on the COVID pandemic, the Biden administration needs Congress to allocate more funding for the federal government, HHS Secretary Xavier Becerra said at a press conference on Friday. “I’m going to lay out to Congress what we can do with what they give us […]
When Is Green Poop a Sign of Infection?
What is green poop? Your doctor may be able to diagnose the cause of green poop by taking a sample of your stool. They’ll send your stool sample to the lab to test for the presence of bacteria or other infections. Poop (also known as stool) comes in a variety of shapes and sizes. As […]